Stem cell retinal implant enters phase 2b testing

Stem cell retinal implant enters phase 2b testing

Researchers at the Roski Eye Institute are testing a stem cell retinal implant as a possible treatment for advanced dry age-related macular degeneration.

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Researchers at the Roski Eye Institute are testing a stem cell retinal implant as a possible treatment for advanced dry age-related macular degeneration.

This new implant combines lab-grown retinal pigment epithelium cells with an ultra-thin support layer making it thinner than a strand of human hair. The outpatient procedure involves the surgeon placing the implant into the retina with the hope of replacing damaged retinal cells and restoring vision.

Initial study results involving rats demonstrated the ability of the cells to regenerate and positive results were also realized using mini pigs. The larger phase 2b clinical trial is now underway at five sites across the United States.

Study subjects range in age from 55 to 90 with advanced dry age-related macular degeneration and geographic atrophy. The participants will be followed for at least one year. Researchers will be looking to see if the implant will take over for the damaged cells and improve the vision for the patients.