The AREDS 2 study, conducted by the National Eye Institute, established a foundation for using specific antioxidants and minerals to support macular health. Eye vitamins based on this research are widely recommended for individuals seeking long-term vision support, especially those over age 50. While the core AREDS 2 formula includes vitamin C, vitamin E, zinc, copper, lutein, and zeaxanthin, not all individuals tolerate each ingredient equally. For this reason, VisiVite offers multiple variations of the AREDS 2 formula, including zinc-free and vitamin E-free options.
What Is the AREDS 2 Formula?
The AREDS 2 formula was developed to provide nutritional support for the macula, the central part of the retina responsible for high-resolution vision. The updated formula replaced beta-carotene with lutein and zeaxanthin—two plant-derived carotenoids concentrated in the macula. These nutrients help filter harmful blue light and neutralize oxidative stress, contributing to the maintenance of healthy visual function over time.
Standard AREDS 2 supplements also include vitamin C, vitamin E, zinc, and copper. However, individual needs may vary. Some people may require formulations without certain ingredients due to genetic factors or medical conditions.
AREDS 2 Zinc-Free Formulas
VisiVite’s AREDS 2 Zinc-Free White Formula is designed for individuals with genetic variations in the complement factor H (CFH) gene. Research suggests that people with certain CFH alleles may not benefit from zinc and may even experience a reduced effect from other antioxidants when zinc is included. The zinc-free version excludes this mineral while retaining key ingredients such as FloraGLO® lutein, OmniXan® zeaxanthin, and natural vitamins C and E. This formulation provides antioxidant support without the inclusion of zinc, allowing for targeted macular care.
AREDS 2 E-Free Formulas
Some individuals may wish to avoid vitamin E, particularly those who are advised to limit its intake due to anticoagulation therapy or personal health considerations. VisiVite’s AREDS 2 E-Free Blue Formula offers a vitamin E-free alternative while maintaining antioxidant support through other nutrients. This formulation includes increased levels of lutein and zeaxanthin, along with bilberry, grape seed extract, alpha lipoic acid, and L-glutathione. These ingredients work synergistically to support retinal health without relying on vitamin E.
Choosing the Right AREDS 2 Eye Supplement
While the original AREDS 2 formula remains the foundation of many eye vitamin products, variations like zinc-free and E-free allow individuals to choose a formulation that aligns with their personal health profile. These tailored options reflect a more personalized approach to nutritional support for vision health. VisiVite’s AREDS 2 line is formulated with clinically studied ingredients and free from synthetic fillers or artificial colors, using clear vegetarian capsules for easy digestion.