Why does VisiVite use 40 mg daily zinc
rather than 80 mg daily zinc?
VisiVite AREDS 2 Gold, E-Free, Select and Chewable Tablet formulas contain 40 mg zinc rather than 80 mg zinc per daily dose due to two reasons:
- The original AREDS study in 2001 found that genitourinary hospitalizations were significantly more frequent in patients receiving 80 mg zinc/2mg copper.
https://jamanetwork.com/journals/jamaophthalmology/fullarticle/268224
- The AREDS2 study found no significant different in outcome when 25 mg daily zinc was compared with 80 mg daily zinc. https://jamanetwork.com/journals/jama/fullarticle/1684847
Why does Visivite use 1 mg daily copper rather than 2 mg daily copper?
At the high levels in AREDS 2 supplements, zinc ingestion may cause anemia by competing with iron at the hemoglobin binding sites. Copper is required not to support macular degeneration, but rather to protect against a zinc-induced anemia. VisiVite uses a Zinc 40 to Copper 1 ratio, exactly as was done in both the AREDS and AREDS 2 research.